Ryan Reynolds, true to his nature, delivered the most perfectly petty response to being replaced as Deadpool, and it’s absolutely brilliant.
The actor recently dropped a mock reaction video that’s equal parts hilarious revenge and promotional genius after learning Neil Patrick Harris would voice the Merc with a Mouth in the upcoming VR game.
Marvel’s Deadpool VR was announced at Summer Game Fest 2025, but the real entertainment came days later when Reynolds decided to settle the score. His response video is a masterclass in how to handle being “replaced” with style, humor, and just the right amount of manufactured outrage.
Ryan Reynolds channels his inner Doogie Howser for maximum pettiness





The revenge video opens with Reynolds sitting at a painfully retro computer, complete with lab coat and glasses that scream 1989.
He’s channeling Doogie Howser, M.D., the show that launched Neil Patrick Harris into stardom as a teenage medical prodigy. The setup alone is comedy gold, but Reynolds takes it further by actually typing out his “personal journal” entries while narrating in that classic Doogie voiceover style.
“Today I learned a lesson about b*ttholes they don’t teach you in medical school,” Reynolds deadpans while pecking away at the keyboard. “People who steal your signature role are the biggest b*ttholes of all.”
The typing is deliberately awkward, like someone who’s never used a computer before, which adds another layer of authenticity to the How I Met Your Mother star’s parody.
The attention to detail is remarkable. Reynolds recreated Doogie’s bedroom setup, complete with the antiquated IBM computer and that distinctive 80s aesthetic. Even Robyn Lively (Blake Lively’s half-sister!) appears as a callback to her role as Michele Farber, Doogie’s love interest on the show.
Reynolds continues his mock tantrum by acknowledging Harris’s talent while maintaining the teenage Doogie persona:
Neil Patrick Harris is an amazing actor with the nurturing voice of an angel, but even though I haven’t hit puberty yet, I still know when you’re getting totally screwed.
The commitment to staying in character while delivering genuine compliments wrapped in manufactured outrage is peak Reynolds.
Summer Game Fest’s cruel joke sets the stage for VR controversy

The Marvel’s Deadpool VR announcement itself came with its own dose of controversy that perfectly matches the character’s chaotic energy.
Geoff Keighley opened the reveal by reading a letter supposedly from Deadpool himself, requesting him to “skip that Silksong trailer” in favor of his industry-shocking “revolutionary VR gaming venture.”
The joke landed like a punch to the gut for Hollow Knight fans who’ve been waiting years for Silksong news.
This wasn’t just a throwaway gag. It was a calculated move that perfectly captured Deadpool‘s tendency to break the fourth wall and mess with audience expectations.
And the fact that it came at the expense of one of gaming’s most anticipated sequels made it even more authentically Deadpool. The character has always thrived on being the villain in someone else’s story, and trolling Silksong fans fits that energy perfectly.
The timing couldn’t have been more brutal either. After all, Hollow Knight: Silksong has become gaming’s white whale, with fans analyzing every industry event for potential news. Having Deadpool essentially steal that moment for his own announcement is the kind of meta-commentary that makes the character so compelling.
Reynolds’s “over-reaction” video is the perfect capstone to this whole promotional cycle. It’s revenge, promotion, and comedy all wrapped into one perfectly executed package that reminds everyone why he owns this character so very completely.
What’s your take on Reynolds’s hilarious response to being replaced in Deadpool VR? Does the parody make you more or less excited for Harris’s take on the character? Drop your thoughts below.
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